Multicenter Observational Study on Metastatic Non-Small Cell Lung Cancer Harboring BRAF Mutations: Focus on Clinical Characteristics and Treatment Outcome of V600E and Non-V600E Subgroups.

Fabiana PerroneGiulia MazzaschiRoberta MinariMichela VerzèCinzia AzzoniLorena BottarelliRita NizzoliMonica PluchinoAnnalisa AltimariElisa GruppioniFrancesca SperandiElisa AndriniGiorgia GuaitoliFederica BertoliniFausto BarbieriStefania BettelliLucia LongoMaria PaganoCandida BonelliElena TagliaviniDavide NicoliAlessandro UbialiAdriano ZangrandiSerena TrubiniManuela ProiettoLetizia GnettiMarcello Tiseo

Published in: Cancers (2022)

Here, we report on real-life data from a retrospective cohort of advanced-NSCLC harboring BRAF alterations. Our study offers relevant clues on survival outcome, therapeutic response, and clinicopathologic correlations of BRAF-mutant NSCLC.

Keyphrases

small cell lung cancer
wild type
metastatic colorectal cancer
advanced non small cell lung cancer
squamous cell carcinoma
brain metastases
electronic health record
clinical trial
cross sectional
machine learning
double blind
deep learning
artificial intelligence
tyrosine kinase