A new synthetic protegrin as a promising peptide with antibacterial activity against MDR Gram-negative pathogens.
Javier Moreno MoralesSalvador GuardiolaClara Ballesté-DelpierreErnest GiraltJordi VilaPublished in: The Journal of antimicrobial chemotherapy (2022)
PLP-3 has potent antimicrobial activity, especially against A. baumannii, while maintaining low haemolysis and toxicity against human cell lines at antimicrobial concentrations. These characteristics make PLP-3 a promising peptide with an interesting therapeutic window.