Patient-centered outcomes in the POLO study of active maintenance olaparib for germline BRCA-mutated metastatic pancreatic cancer.
Hedy Lee KindlerHyun Kyoo YooRobert HettleKaren Y CuiSeongjung JooGershon Y LockerTalia GolanPublished in: Cancer (2023)
These results support the previous findings that maintenance olaparib significantly improves PFS relative to placebo without compromising HRQOL and demonstrate that the clinically meaningful benefits of olaparib persist even when symptoms of toxicity are considered.