Molecular and clinicopathological differences between depressed and protruded T2 colorectal cancer.
Kenichi MochizukiShin-Ei KudoKazuki KatoKoki KudoYushi OgawaYuta KouyamaYuki TakashinaKatsuro IchimasaTaro ToboTakeo ToshimaYuichi HisamatsuYusuke YonemuraTakaaki MasudaHideyuki MiyachiFumio IshidaTetsuo NemotoKoshi MimoriPublished in: PloS one (2022)
Depressed-type T2 CRC had a significant association with CMS4, showing more malignant pathological findings such as lymphatic invasion than the protruded-type, which could explain the reported association between CMS4 CRC and poor prognosis.