The impact of maintenance therapy on sleep-wake rhythms and cancer-related fatigue in pediatric acute lymphoblastic leukemia.

Lindsay M H Steur Gertjan J L KaspersE J W van SomerenN K A van EijkelenburgI M van der SluisN DorsC van den BosW J E TissingM A GrootenhuisRaphaele R L van Litsenburg

Published in: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer (2020)

Sleep-wake rhythms are disturbed, physical activity levels lower, and cancer-related fatigue levels higher during maintenance therapy. Interventions aimed to enhance sleep-wake rhythms during maintenance therapy could improve cancer-related fatigue. Families should be supported in coping with the additional burden of dexamethasone treatment to improve well-being of ALL patients.

Keyphrases

physical activity
sleep quality
acute lymphoblastic leukemia
depressive symptoms
newly diagnosed
ejection fraction
body mass index
stem cells
low dose
bone marrow
replacement therapy
social support
chronic kidney disease
combination therapy
cell therapy
patient reported
smoking cessation