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Evaluation of the Antidiarrheal Activity of Hydromethanol Crude Extracts of Ruta chalepensis and Vernonia amygdalina in Mice.

Amsalu DeguBelayneh KefaleDiriba Alemayehu GadisaGobezie Temesgen Tegegne
Published in: Evidence-based complementary and alternative medicine : eCAM (2020)
The present study demonstrated that the crude leaves extract of Ruta chalepensis (200 and 400 mg/kg.bw) and Vernonia amygdalina (400 mg/kg.bw) possessed significant antidiarrheal activity in the castor oil-induced diarrheal model.
Keyphrases
  • oxidative stress
  • high glucose
  • diabetic rats
  • type diabetes
  • fatty acid
  • drug induced
  • metabolic syndrome
  • skeletal muscle
  • insulin resistance
  • endothelial cells
  • adipose tissue
  • anti inflammatory