Identification of regulatory mRNA and microRNA for differentiation into cementoblasts and periodontal ligament cells.

Tomoyuki IwataNoriyoshi MizunoTakayoshi NagaharaEri Kaneda-IkedaMikihito KajiyaMasae KitagawaKatsuhiro TakedaMinami YoshiokaRyoichi YagiTakashi TakataHidemi Kurihara

Published in: Journal of periodontal research (2020)

HCEM and HPL cells show characteristic mRNA and miRNA profiles. In particular, these cells have specific miR-383, miR-628-5p, and ETV1 expression patterns, and these genes interact with each other. Therefore, miR-383, miR-628-5p, and ETV1 are key genes involved in cementogenesis or HPL cell differentiation.

Keyphrases

induced apoptosis
cell cycle arrest
cell proliferation
long non coding rna
acute lymphoblastic leukemia
endoplasmic reticulum stress
poor prognosis
binding protein
pi k akt