Chronic and Neurotropic: A Paradigm-Challenging Case of Dengue Virus Encephalitis in a Patient With Advanced HIV Infection.

Tina M MarinelliJeffrey MastersMichael E BucklandMaggie LeeWilliam RawlinsonKi Wook KimNicolas UrriolaSebastiaan van Hal

Published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2024)

A 32-year-old female with advanced human immunodeficiency virus infection presented to an Australian hospital with subacute, worsening symptoms of encephalitis. Metagenomic sequencing and Dengue NS3 antigen staining of brain tissue confirmed active dengue virus (DENV) encephalitis. The most recent possible DENV exposure was months prior in West Africa, indicating chronicity.

Keyphrases

dengue virus
zika virus
aedes aegypti
endothelial cells
healthcare
case report
white matter
single cell
induced pluripotent stem cells
antiretroviral therapy
sleep quality
pluripotent stem cells
cerebral ischemia
adverse drug
depressive symptoms
brain injury
drug induced