7 hub genes serve as excellent independent biomarkers for molecular diagnosis, and the neural network diagnostic model can accurately distinguish BRCA patients. In addition, based on the expression levels of these seven genes in BRCA patients, two subtypes can be reliably identified: BRCA subtype 1 and BRCA subtype 2, and these two subtypes showed significant differences in BRCA patient survival prognosis, proportion of immune cells, and expression levels of immune cells. Among them, patients with subtype 1 of BRCA had a poor prognosis.
Keyphrases
- poor prognosis
- end stage renal disease
- long non coding rna
- ejection fraction
- newly diagnosed
- breast cancer risk
- chronic kidney disease
- genome wide
- neural network
- type diabetes
- metabolic syndrome
- insulin resistance
- weight loss
- bioinformatics analysis
- gene expression
- adipose tissue
- physical activity
- dna methylation
- weight gain
- case report
- binding protein
- patient reported
- genome wide analysis