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Safety and efficacy of semaglutide once weekly vs sitagliptin once daily, both as monotherapy in Japanese people with type 2 diabetes.

Yutaka SeinoYasuo TerauchiTakeshi OsonoiDaisuke YabeNobuyuki AbeTomoyuki NishidaJeppe ZachoShizuka Kaneko
Published in: Diabetes, obesity & metabolism (2017)
In Japanese people with T2D, more TEAEs were reported with semaglutide than with sitagliptin; however, the semaglutide safety profile was similar to that of other glucagon-like peptide-1 receptor agonists. Semaglutide significantly reduced HbA1c and body weight compared with sitagliptin.
Keyphrases
  • body weight
  • combination therapy
  • open label
  • randomized controlled trial
  • clinical trial