Safety and effectiveness of interference RNA (RNAi) based therapeutics in cardiac failure: A systematic review.
Muhammad Nabeel SaddiqueMaria QadriNoor Ul AinEesha FarhanFatima ShahidJaveria BenyaminMuhammad Atif BashirHritvik JainJaved IqbalPublished in: Heart & lung : the journal of critical care (2024)
RNAi therapeutics are novel treatment option for improving cardiac function because their high target specificity, ability to target genes that conventional drugs struggle to reach and potential for long-lasting effects. Further research on optimizing delivery methods, improving target specificity, evaluating long-term safety profiles and cost-effectiveness to fully realize their potential.