Stage IC grade 1 endometrioid adenocarcinoma of the ovary: assessment of post-operative chemotherapy de-escalation.

Sabrina M WollMatthew W LeeMonica K NeumanChristian PinoMaximilian KlarLynda D RomanJason D Wright Koji Matsuo

Published in: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society (2024)

The results of this population-based study may partially support the current clinical practice guidelines for post-operative chemotherapy omission as a possible option for patients with stage IC grade 1 endometrioid adenocarcinoma of the ovary for those who had lymph node evaluation. Observed data were also supportive for node-evaluated grade 2 tumors, warranting further evaluation.

Keyphrases

lymph node
locally advanced
neoadjuvant chemotherapy
squamous cell carcinoma
endometrial cancer
rectal cancer
radiation therapy
clinical trial
electronic health record
open label
randomized controlled trial
deep learning
clinical evaluation