Bivalent therapeutic vaccine against HPV16/18 genotypes consisting of a fusion protein between the extra domain A from human fibronectin and HPV16/18 E7 viral antigens.
Laura ArribillagaIciar EcheverriaViriginia BelsueTimothy GomezTeresa LozanoNoelia CasaresLorea VillanuevaSonia Domingos-PereiraPedro J RomeroDenise Nardelli-HaefligerSandra Hervás-StubbsPablo SarobeMaría Josefa RodriguezJosé L CarrascosaThomas ZürcherJuan Jose LasartePublished in: Journal for immunotherapy of cancer (2021)
Our results suggest that this therapeutic vaccine formulation may be an effective treatment for cervical tumors that do not respond to current therapies.