Targeting the YAP-TEAD interaction interface for therapeutic intervention in glioblastoma.
Jacquelyn T SaundersBrent HolmesAngelica Benavides-SerratoSunil KumarRobert N NishimuraJoseph F GeraPublished in: Journal of neuro-oncology (2021)
These results demonstrate that blockade of YAP-TEAD association is a viable therapeutic strategy for glioblastoma. On the basis of these favorable preclinical studies further clinical studies are warranted.