Nitric Oxide Inhalation Therapy Attenuates Postoperative Hypoxemia in Obese Patients with Acute Type A Aortic Dissection.
Ping ZhengDingsheng JiangChun LiuXiang WeiShiliang LiPublished in: Computational and mathematical methods in medicine (2022)
Low-dose iNO could improve oxygenation and shorten mechanical ventilation and ICU stay in patients with hypoxemia after ATAAD surgery, but without significant side effects or increase in postoperative mortality or morbidity. These findings provide a basis for a randomized multicenter controlled trial to assess the efficacy of iNO in the treatment of hypoxemia after ATAAD surgery.
Keyphrases
- mechanical ventilation
- minimally invasive
- aortic dissection
- low dose
- nitric oxide
- intensive care unit
- coronary artery bypass
- acute respiratory distress syndrome
- patients undergoing
- respiratory failure
- surgical site infection
- metabolic syndrome
- adipose tissue
- double blind
- high dose
- cardiovascular events
- study protocol
- weight loss
- randomized controlled trial
- extracorporeal membrane oxygenation
- cardiovascular disease
- clinical trial
- risk factors
- stem cells
- nitric oxide synthase
- mesenchymal stem cells