5-Year results from the prospective European multi-centre study on decellularized homografts for pulmonary valve replacement ESPOIR Trial and ESPOIR Registry data.

Dmitry Bobylev Alexander Horke Dietmar BoethigMark HazekampBart Meyns Filip R Rega Hitendu DaveMartin SchmiadyAnatol CiubotaruEduard CheptanaruVladimiro L VidaMassimo PadalinoVictor TsangRamadan JashariGuenther Laufer Martin Andreas Alexandra AndreevaIgor TudoracheSerghei CebotariAxel HaverichSamir Sarikouch

Published in: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery (2022)

The 5-year data of the prospective ESPOIR Trial show excellent performance for DPH and low rates of adverse events. ESPOIR Registry data up to 15 years, including a matched comparison with CH, demonstrated statistically significant better freedom from explantation.

Keyphrases

electronic health record
big data
study protocol
clinical trial
phase iii
pulmonary hypertension
aortic valve
heart failure
randomized controlled trial
data analysis
left ventricular
open label
double blind