Effectiveness of high-flow nasal cannula therapy on clinical outcomes in adults with COVID-19: A systematic review.
Daiana Gonçalves ArrudaGeorge Alvício KielingLucélia Luna Melo-DiazPublished in: Canadian journal of respiratory therapy : CJRT = Revue canadienne de la therapie respiratoire : RCTR (2023)
In adult patients hospitalized with COVID-19, HFNC may prove effective in reducing the rate of orotracheal intubation. The ratio of the oxygen saturation index was the parameter most examined as a predictor of HFNC success. Low-level research designs, inherent study weaknesses and inconsistent findings made it impossible to conclude whether HFNC reduces ICU length of stay or mortality. Future studies should employ higher level research designs.
Keyphrases
- coronavirus disease
- sars cov
- randomized controlled trial
- intensive care unit
- systematic review
- cardiovascular events
- extracorporeal membrane oxygenation
- risk factors
- coronary artery disease
- case control
- finite element analysis
- obstructive sleep apnea
- mesenchymal stem cells
- positive airway pressure
- acute respiratory distress syndrome
- sleep apnea