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Tolerability and effectiveness of palbociclib in older women with metastatic breast cancer.

Joosje C BaltussenSimon P MooijaartAnnelie J E VulinkDanny HoutsmaWendy M Van der DeureElsbeth M WestermanHendrika M OosterkampLeontine E A M M SpieringsFrederiek van den BosNienke A de GlasJohanneke E A Portielje
Published in: Breast cancer research and treatment (2024)
Although grade 3-4 toxicity and dose reductions occurred frequently, most were expected and managed by dose reductions, showing that palbociclib is generally well tolerated and thus represents a valuable treatment option in the older population.
Keyphrases
  • metastatic breast cancer
  • community dwelling
  • middle aged
  • physical activity
  • randomized controlled trial
  • systematic review
  • oxidative stress
  • open label
  • clinical trial
  • combination therapy
  • placebo controlled