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The role of stathmin expression in the differential diagnosis, prognosis, and potential treatment of ovarian sex cord-stromal tumors.

Adam ŠafandaMichaela Kendall BártůRomana MichálkováMarián ŠvajdlerTetiana ShatokhinaJan LacoRadoslav MatějGábor MéhesJana DrozenováJitka HausnerováZuzana ŠpůrkováJozef ŠkardaMária HácováMonika NáležinskáPavel DundrKristýna Němejcova
Published in: Diagnostic pathology (2024)
The results of our study indicate that stathmin is neither a prognostic marker nor suitable for the differential diagnosis of challenging cases of ovarian sex cord-stromal tumors. However, its predictive value may be theoretically significant, as a decrease in stathmin expression potentialy influences response to chemotherapy treatment.
Keyphrases
  • poor prognosis
  • bone marrow
  • radiation therapy
  • squamous cell carcinoma
  • risk assessment