Sex-dependent vulnerability for Wistar rats model following intranasal instillation with Klebsiella pneumoniae ATCC 43816 causing lobar pneumonia.
Patrick Hervé Diboue BetoteEsther Del Florence Ndedi MoniSonia Raïssa Gayap MatchuenkamSandrine Suzanne Bayengue BeackRodrigue FifenRaogo OuedraogoGabriel A AgborRasmané SemdeNga NnangaMaximilienne Ascension NyeguePublished in: Pneumonia (Nathan Qld.) (2024)
The results obtained highlighted the gender-dependency in the physiopathogenesis processes of K. pneumoniae ATCC 43816 induced-lobar pneumonia, in Wistar rats. Female Wistar rats' susceptibility is useful in studying pathology and in preclinical trial investigations of new treatments for infectious pneumonia.
Keyphrases
- klebsiella pneumoniae
- multidrug resistant
- escherichia coli
- respiratory failure
- community acquired pneumonia
- climate change
- clinical trial
- high glucose
- study protocol
- mental health
- diabetic rats
- randomized controlled trial
- phase iii
- stem cells
- drug induced
- oxidative stress
- intensive care unit
- endothelial cells
- respiratory tract