Sex differences in imaging and clinical characteristics of patients from the WAKE-UP trial.
Anke WoutersLauranne ScheldemanHannelore LiessensPatrick DupontFlorent BoutitieBastian ChengMartin EbingerMatthias EndresJochen B FiebachChristian GerloffKeith W MuirNorbert NighoghossianSalvador PedrazaClaus Z SimonsenVincent ThijsGötz ThomallaRobin LemmensPublished in: European journal of neurology (2022)
As in many other stroke trials, more men than women were included in the WAKE-UP trial, but the presence of a visual DWI-FLAIR mismatch and the relative FLAIR signal intensity did not differ between the sexes. The treatment effect of alteplase was not modified by sex.
Keyphrases
- end stage renal disease
- study protocol
- clinical trial
- phase iii
- ejection fraction
- newly diagnosed
- chronic kidney disease
- phase ii
- high resolution
- atrial fibrillation
- polycystic ovary syndrome
- randomized controlled trial
- computed tomography
- high intensity
- mass spectrometry
- pregnant women
- acute ischemic stroke
- magnetic resonance
- diffusion weighted imaging
- adipose tissue
- subarachnoid hemorrhage
- replacement therapy
- contrast enhanced