Neutrophil gelatinase-associated lipocalin distribution in preterm newborns without acute kidney injury as defined by a reference method.
Aurélie De MulPaloma ParvexAlexandra Wilhelm-BalsPublished in: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians (2021)
In this preterm newborn's series without AKI, the median uNGAL and its high variability are in accordance with published reference ranges. Correlation between uNGAL and gestational age exists, as well as gender impact. Newborns exposed to different renal insults present higher uNGAL values, suggesting potential undetected tubular toxicity or reflecting NGAL production in case of inflammatory or ischemic processes.
Keyphrases
- gestational age
- acute kidney injury
- birth weight
- preterm birth
- cardiac surgery
- oxidative stress
- low birth weight
- mental health
- ischemia reperfusion injury
- human health
- systematic review
- randomized controlled trial
- pregnant women
- physical activity
- preterm infants
- risk assessment
- brain injury
- subarachnoid hemorrhage
- climate change