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siRNA-mediated downregulation of BATF3 diminished proliferation and induced apoptosis through downregulating c-Myc expression in chronic myelogenous leukemia cells.

Reza DabbaghipourVahid Khaze ShahgoliSahar SafaeiMohammad AminiSmb TabeiDariush ShanehbandiOmid Rahbar FarzamBehzad BaradaranMona Entezam
Published in: Molecular biology reports (2024)
The findings of this research illustrated the suppression of BATF3 as an effective targeted therapy strategy for CML.
Keyphrases
  • induced apoptosis
  • signaling pathway
  • endoplasmic reticulum stress
  • oxidative stress
  • pi k akt
  • poor prognosis
  • acute myeloid leukemia
  • cell proliferation
  • cell cycle arrest
  • hyaluronic acid
  • cell death
  • drug induced