Login / Signup

Genome Sequences of Diverse Human Cytomegalovirus Strains with Utility in Drug Screening and Vaccine Evaluation.

Kathleen CorcoranCarly J SherrodEllen F PerkowskiJordan TexierFengsheng LiI-Ming WangMichael McVoyTong Ming FuDirk P Dittmer
Published in: Genome announcements (2017)
Cytomegalovirus displays genetic heterogeneity, which has implications for antiviral and vaccine development. Many studies have focused on laboratory isolates that have been extensively adapted for growth on fibroblasts. Here, we report whole-genome sequences for 10 human cytomegalovirus (HCMV) strains that readily grow on ARPE-19 human retinal pigment epithelial cells.
Keyphrases
  • endothelial cells
  • induced pluripotent stem cells
  • escherichia coli
  • pluripotent stem cells
  • genome wide
  • multidrug resistant
  • single cell
  • gene expression
  • dna methylation
  • genetic diversity
  • copy number