Irisin promotes odontogenic differentiation and angiogenic potential in human dental pulp cells.

J W SonSung-Hyeon Choi Ji-Hyun Jang Jeong Tae Koh Won-Mann Oh Yun-Chan Hwang Bin-Na Lee

Published in: International endodontic journal (2020)

Irisin promoted odontogenic differentiation and mineralization and has the potential for angiogenesis through activation of the MAPK and Akt signalling pathways in HDPCs.

Keyphrases

endothelial cells
signaling pathway
induced apoptosis
cell cycle arrest
cell proliferation
human health
pi k akt
vascular endothelial growth factor
cell death
risk assessment
endoplasmic reticulum stress
pluripotent stem cells
climate change