Leveraging Human Genetics to Identify Safety Signals Prior to Drug Marketing Approval and Clinical Use.
Rebecca N JeromeMeghan Morrison JolyNan KennedyJana K Shirey-RiceDan M RodenGordon R BernardKenneth J HolroydJoshua C DennyJill M PulleyPublished in: Drug safety (2021)
By connecting and integrating in vivo and in silico data, SA-PheWAS offers an opportunity to supplement current methods for predicting or confirming safety signals associated with therapeutic agents.