Mid-Term and Long-Term Outcomes of Peroral Endoscopic Myotomy for the Treatment of Achalasia: A Systematic Review and Meta-Analysis.

Han ZhangXinyi ZengShu HuangLei ShiHuifang XiaJiao JiangWensen RenYan PengMuhan LüXiao-Wei Tang

Published in: Digestive diseases and sciences (2022)

POEM is associated with a long-term clinical success of 82.2% after 5 years of follow-up. Randomized control trials comparing POEM with laparoscopic Heller myotomy or pneumatic dilation with longer follow-up periods are needed to further demonstrate the long-term safety and efficacy of POEM.

Keyphrases

double blind
open label
robot assisted
clinical trial
placebo controlled
phase iii
randomized controlled trial
combination therapy
minimally invasive
study protocol
smoking cessation