Expert consensus on multidisciplinary therapy of colorectal cancer with lung metastases (2019 edition).
Jian LiYing YuanFan YangYi WangXu ZhuZhenghang WangShu ZhengDesen WanJie HeJianping WangYi BaChunmei BaiLi BaiWei BaiFeng BiKaican CaiMuyan CaiSanjun CaiGong ChenKeneng ChenLin ChenPengju ChenPan ChiGuanghai DaiYanhong DengKefeng DingQingxia FanWeijia FangXuedong FangFengyi FengChuangang FuQihan FuYanhong GuYulong HeBaoqing JiaKewei JiangMaode LaiPing LanEnxiao LiDechuan LiJin LiLeping LiMing LiShaolei LiYexiong LiYongheng LiZhongwu LiXiaobo LiangZhiyong LiangFeng LinGuole LinHongjun LiuJianzhong LiuTianshu LiuYunpeng LiuHongming PanZhizhong PanHaiping PeiMeng QiuXiujuan QuLi RenZhanlong ShenWeiqi ShengChun SongLijie SongJianguo SunLingyu SunYingshi SunYuan TangMin TaoChang WangHaijiang WangJun WangShubin WangXicheng WangXishan WangZiqiang WangAiwen WuNan WuLijian XiaYi XiaoBaocai XingBin XiongJianmin XuJianming XuNong XuRuihua XuZhongfa XuYue YangHongwei YaoYingjiang YeYonghua YuYueming YuJinbo YueJingdong ZhangJun ZhangSuzhan ZhangWei ZhangYanqiao ZhangZhen ZhangZhongtao ZhangLin ZhaoRen ZhaoFuxiang ZhouJian ZhouJing JinJin GuLin ShenPublished in: Journal of hematology & oncology (2019)
The lungs are the second most common site of metastasis for colorectal cancer (CRC) after the liver. Rectal cancer is associated with a higher incidence of lung metastases compared to colon cancer. In China, the proportion of rectal cancer cases is around 50%, much higher than that in Western countries (nearly 30%). However, there is no available consensus or guideline focusing on CRC with lung metastases. We conducted an extensive discussion and reached a consensus of management for lung metastases in CRC based on current research reports and the experts' clinical experiences and knowledge. This consensus provided detailed approaches of diagnosis and differential diagnosis and provided general guidelines for multidisciplinary therapy (MDT) of lung metastases. We also focused on recommendations of MDT management of synchronous lung metastases and initial metachronous lung metastases. This consensus might improve clinical practice of CRC with lung metastases in China and will encourage oncologists to conduct more clinical trials to obtain high-level evidences about managing lung metastases.