High expression of the ferroptosis-associated MGST1 gene in relation to poor outcome and maladjusted immune cell infiltration in uterine corpus endometrial carcinoma.

Published in: Journal of clinical laboratory analysis (2022)

Elevated MGST1 expression is related to tumour development and poor prognosis, as well as dysregulated infiltration of immune cells in UCEC, which can be a potential prognostic indicator and ferroptosis-based immunotherapy target.

Keyphrases

poor prognosis
long non coding rna
cell death
copy number
genome wide
risk assessment
transcription factor
endometrial cancer
binding protein