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miRNAs as potential biomarkers for subclinical atherosclerosis in Sjögren's disease.

Nadine ZehrfeldMalin AbelmannSabrina BenzTabea SeeligerFiona EngelkeThomas SkripuletzChristian BaerThomas ThumTorsten WitteKristina SonnenscheinDiana ErnstAnselm Arthur Derda
Published in: RMD open (2024)
In conclusion, patients with SjD demonstrated differences in their expression of miRNAs linked to regulation of endothelial function. Reduction of specific miRNAs was associated with increased cardiovascular risk, suggesting a potentially protective role for these miRNAs. Furthermore, miR-92a-3p could be helpful for molecular detection of early-stage atherosclerosis and increased cardiovascular risk in SjD.
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