Neurocognitive effects of 3 mA prefrontal electrical stimulation in schizophrenia: A randomized sham-controlled tDCS-fMRI study protocol.
Amir-Homayun HallajianKiomars SharifiReza RostamiFahimeh SaeedShirin Mokarian RajabiNegin ZangenehniaZahra AminiZahra AskariFidel Vila-RodriguezMohammad Ali SalehinejadPublished in: PloS one (2024)
The results of this study are helpful in optimizing tDCS protocols in SCZ and inform us of neurocognitive mechanisms underlying 3 mA stimulation. This study will additionally provide initial safety and efficacy data on a 3 mA tDCS protocol to support larger clinical trials. Positive results could lead to rapid and broader testing of a promising tool for debilitating symptoms that affect the majority of patients with SCZ. The results will be made available through publications in peer-reviewed journals and presentations at national and international conferences.
Keyphrases
- clinical trial
- transcranial direct current stimulation
- bipolar disorder
- randomized controlled trial
- study protocol
- functional connectivity
- spinal cord injury
- working memory
- systematic review
- resting state
- machine learning
- open label
- physical activity
- quality improvement
- depressive symptoms
- double blind
- sensitive detection
- deep learning
- placebo controlled