The efficacy and safety of hydroxychloroquine for COVID-19 prophylaxis: A systematic review and meta-analysis of randomized trials.
Kimberley A LewisDipayan ChaudhuriFayez Ebrahim AlshamsiKallirroi Laiya CarayannopoulosKarin DearnessZain ChaglaWaleed Alhazzaninull nullPublished in: PloS one (2021)
Although pharmacologic prophylaxis is an attractive preventive strategy against COVID-19, the current body of evidence failed to show clinical benefit for prophylactic hydroxychloroquine and showed a higher risk of adverse events when compared to placebo or no prophylaxis.