Validation of a new assay for α-synuclein detection in cerebrospinal fluid.

Marthe Gurine FørlandAnnika ÖhrfeltLinn Silje OftedalOle-Bjørn TysnesJan Petter LarsenKaj BlennowHenrik ZetterbergGuido AlvesJohannes Lange

Published in: Clinical chemistry and laboratory medicine (2017)

We present a novel assay based on freely available components to quantify total α-synuclein in CSF as an additional method for α-synuclein as a biomarker in neurodegenerative diseases. The assay convinces with its simple and convenient protocol paired with high sensitivity.

Keyphrases

cerebrospinal fluid
high throughput
randomized controlled trial
single cell
label free
quantum dots