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Classification of protein-protein association rates based on biophysical informatics.

Kalyani DhusiaYinghao Wu
Published in: BMC bioinformatics (2021)
In summary, this study demonstrated that a new modeling framework that combines biophysical simulations with bioinformatics approaches is able to identify protein-protein interactions with low association rates from those with higher association rates. This method thereby can serve as a useful addition to a collection of existing experimental approaches that measure biomolecular recognition.
Keyphrases
  • protein protein
  • small molecule
  • machine learning
  • deep learning