The Role of Probe-Based Confocal Laser Endomicroscopy (pCLE) in the Diagnosis of Sustained Clinical Complete Response Under Watch-and-Wait Strategy After Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Adenocarcinoma: a Score Validation.
Adriana Vaz Safatle-RibeiroUlysses RibeiroJohn LataElisa Ryoka BabaLuciano LenzBruno da Costa MartinsFábio KawagutiRenata Nobre MouraCaterina PennacchiCarla GusmonMarcelo Simas de LimaGustavo Andrade de PauloCaio Sérgio NahasCarlos Frederico MarquesAntônio Rocco ImperialeGuilherme C CottiFauze Maluf-FilhoSérgio Carlos NahasPublished in: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract (2023)
pCLE scoring system based on epithelial and vascular features improved the diagnosis of sustained cCR and might be recommended during follow-up. pCLE might add some valuable contribution for identifying local regrowth. Trial Registration This protocol was registered at the Clinical Trials (ClinicalTrials.gov identifier NCT02284802).