Silencing of miR-182 is associated with modulation of tumorigenesis through apoptosis induction in an experimental model of colorectal cancer.

Lisa PerilliSofia TessarolloLaura AlbertoniMatteo CurtarelloAnna PastòEfrem BrunettiMatteo FassanMassimo RuggeStefano IndraccoloAlberto AmadoriStefania BortoluzziPaola Zanovello

Published in: BMC cancer (2019)

Altogether, these data indicate that increased miR-182 expression may promote cell proliferation, suppress the apoptotic pathway and ultimately confer aggressive traits on CRC cells.

Keyphrases

cell proliferation
cell cycle arrest
pi k akt
cell death
long non coding rna
induced apoptosis
poor prognosis
cell cycle
endoplasmic reticulum stress
long noncoding rna
oxidative stress
electronic health record
big data
gene expression
machine learning
binding protein
anti inflammatory
dna methylation
deep learning