Redefining the strategy for the use of COMT inhibitors in Parkinson's disease: the role of opicapone.

Peter JennerJosé-Francisco RochaJoaquim José FerreiraOlivier RascolPatrício Soares-da-Silva

Published in: Expert review of neurotherapeutics (2021)

This review argues for a shift in the positioning of COMT inhibition with opicapone in the PD algorithm and lays out a pathway for proving its effectiveness in early disease.

Keyphrases

randomized controlled trial
systematic review
machine learning