The present study provides evidence that the protective effects of MnSOD in irradiated HaCaT cells may be related to the inhibition of ferroptosis. The multi-site injections of pMnSOD had clear therapeutic and preventive effects on radiation-induced skin injury in rats. pMnSOD may have therapeutic value for the treatment of radiation-induced skin injury.
Keyphrases
- radiation induced
- radiation therapy
- soft tissue
- cell death
- wound healing
- endothelial cells
- cell cycle arrest
- escherichia coli
- platelet rich plasma
- signaling pathway
- ultrasound guided
- induced pluripotent stem cells
- cell proliferation
- pi k akt
- combination therapy
- pluripotent stem cells
- smoking cessation
- oxidative stress