Calcitriol Treatment Is Safe and Increases Frataxin Levels in Friedreich Ataxia Patients.

Berta Alemany-PernaJordi TamaritElisa CabiscolFabien DelaspreAlbert MiguelaJoana Maria Huertas-PonsAna Quiroga-VarelaMiguel Merchan RuizDaniel López DomínguezLluís Ramió I TorrentàDavid GenísJoaquim Ros

Published in: Movement disorders : official journal of the Movement Disorder Society (2024)

Calcitriol dosage used (0.25 mcg/24 h) is safe for FRDA patients, and it increases frataxin levels. We cannot rule out that higher doses administered longer could yield neurological benefits. © 2024 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
peritoneal dialysis
prognostic factors
randomized controlled trial
systematic review
early onset
patient reported outcomes
blood brain barrier