Login / Signup

Co-Catalyzed Synthesis of N-Sulfonylcarboxamides from Carboxylic Acids and Sulfonyl Azides.

Yue FangZheng-Yang GuShun-Yi WangJin-Ming YangShun-Jun Ji
Published in: The Journal of organic chemistry (2018)
A Co-catalyzed effective synthesis of N-sulfonylcarboxamides from the reaction of carboxylic acids and organic azides in the presence of isocyanide has been developed. The protocol has the advantages of short time, low temperature, and being oxidant-free, which provides a new and simple approach for the synthesis of N-sulfonylcarboxamides in good to excellent yields with a broad substrate scope.
Keyphrases
  • room temperature
  • randomized controlled trial
  • anti inflammatory