Allergen-free extracts from birch, ragweed, and hazel pollen activate human and guinea-pig submucous and spinal sensory neurons.

Sabine BuhnerStefanie SchäuffelePieter Giesbertz Ihsan Ekin DemirFlorian ZellerClaudia Traidl-Hoffman Michael Schemann Stefanie Gilles

Published in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2023)

Allergen-free APEs from birch, ragweed, and hazel evoked strong nerve activation. Altered nerve-immune signaling as a result of severe pollen exposure could be a pathophysiological feature of allergic and non-allergic gut inflammation.

Keyphrases

allergic rhinitis
spinal cord
endothelial cells
oxidative stress
peripheral nerve
machine learning
early onset
deep learning
pluripotent stem cells
drug induced
cell wall