Cardiovascular risk burden, dementia risk and brain structural imaging markers: a study from UK Biobank.

Yaying CaoGaohong ZhuChengwu FengJing ChenWei GanYuan MaYonghua HuKlodian DhanaTrudy VoortmanJie ShenTing LiYan ZhengChangzheng YuanGeng Zong

Published in: General psychiatry (2024)

Our findings suggest that the positive association of cardiovascular risk burden with dementia risk also applies to major dementia subtypes. The association of cardiovascular risk burden with all-cause dementia is largely independent of CVD onset and genetic predisposition to dementia.

Keyphrases

mild cognitive impairment
cognitive impairment
high resolution
risk factors
gene expression
genome wide
cross sectional
dna methylation
copy number
resting state
photodynamic therapy
blood brain barrier