Vitamin D affects the risk of disease activity in multiple sclerosis.

Antonino GiordanoFerdinando ClarelliBéatrice PignoletElisabetta MasciaMelissa SorosinaKaalindi MisraLaura FerrèFlorence BucciarelliAli ManouchehriniaLucia MoiolaVittorio Martinelli Maria Assunta RoccaRoland LiblauMassimo FilippiFederica Esposito

Published in: Journal of neurology, neurosurgery, and psychiatry (2024)

VitD levels before DMT start affect the risk of disease activity in MS. Genetic predisposition to higher VitD levels confers a lower risk of disease activity and is associated with delayed MS onset. Our work prompts future prospective studies regarding VitD supplementation and lifestyle interventions to hamper disease activity in MS.

Keyphrases

disease activity
multiple sclerosis
systemic lupus erythematosus
rheumatoid arthritis
rheumatoid arthritis patients
ankylosing spondylitis
mass spectrometry
juvenile idiopathic arthritis
ms ms
physical activity
white matter
cardiovascular disease
metabolic syndrome
type diabetes
current status
weight loss