There Is Life After the UK Clozapine Central Non-Rechallenge Database.

Ebenezer OloyedeCecilia CasettaOlubanke DzahiniAviv SegevFiona GaughranSukhi ShergillAlek MijovicMarinka HelthuisEromona WhiskeyJames Hunter MacCabeDavid Taylor

Published in: Schizophrenia bulletin (2021)

Implementation of the updated FDA's monitoring criteria in the United Kingdom would significantly reduce clozapine discontinuation due to hematological reasons. The evidence suggests an urgent need for revising the UK clozapine monitoring guidelines to improve outcomes in treatment-resistant schizophrenia.

Keyphrases

cross sectional
bipolar disorder
primary care
healthcare
clinical practice
emergency department
adverse drug
adipose tissue
drug induced