Login / Signup

Forward genetic screen of human transposase genomic rearrangements.

Anton G HenssenEileen JiangJiali ZhuangLuca PinelloNicholas D SocciRichard KocheMithat GonenCamila M VillasanteScott A ArmstrongDaniel E BauerZhiping WengAlex Kentsis
Published in: BMC genomics (2016)
The discovered PSS motifs and high-throughput forward chemical genomic screening approach should prove useful for the elucidation of endogenous genome remodeling activities of PGBD5 and other domesticated human DNA transposases and recombinases.
Keyphrases
  • high throughput
  • endothelial cells
  • copy number
  • induced pluripotent stem cells
  • genome wide
  • dna methylation
  • single molecule