Alex Kentsis (A Kentsis)

Publication Activity (10 Years)

Years Active: 2014-2024
Publications (10 Years): 42

Top Topics

Acute Myeloid Leukemia

Top Venues

Cancer discovery

Journal of proteome research

bioRxiv : the preprint server for biology

Science advances

This page only lists publications with an associated author ORCID identifier.

Publications

Alex Kentsis
Toward a Unified Theory of Why Young People Develop Cancer. Cold Spring Harbor perspectives in medicine (2024)
Ning Wang, Nicole A Mcneer, Elliot O Eton, Josh Fass, Alex Kentsis
Proteomic Barcoding Platform for Macromolecular Screening and Delivery. Journal of proteome research 23 (6) (2024)
Yaniv Kazansky, Helen S Mueller, Daniel Cameron, Phillip Demarest, Nadia Zaffaroni, Noemi Arrighetti, Valentina Zuco, Prabhjot S Mundi, Yasumichi Kuwahara, Romel Somwar, Rui Qu, Andrea Califano, Elisa de Stanchina, Filemon Dela Cruz, Andrew L Kung, Mrinal M Gounder, Alex Kentsis
Epigenetic targeting of PGBD5-dependent DNA damage in SMARCB1-deficient sarcomas. bioRxiv : the preprint server for biology (2024)
Makiko Yamada, Ross R Keller, Rodrigo Lopez Gutierrez, Daniel Cameron, Hiromichi Suzuki, Reeti Sanghrajka, Jake Vaynshteyn, Jeffrey Gerwin, Francesco Maura, William Hooper, Minita Shah, Nicolas Robine, Phillip Demarest, N Sumru Bayin, Luz Jubierre Zapater, Casie Reed, Steven Hébert, Ignas Masilionis, Ronan Chaligné, Nicholas D Socci, Michael D Taylor, Claudia L Kleinman, Alexandra L Joyner, G Praveen Raju, Alex Kentsis
Childhood cancer mutagenesis caused by transposase-derived PGBD5. Science advances 10 (12) (2024)
Yaniv Kazansky, Helen S Mueller, Daniel Cameron, Phillip Demarest, Nadia Zaffaroni, Noemi Arrighetti, Valentina Zuco, Prabhjot S Mundi, Yasumichi Kuwahara, Romel Somwar, Rui Qu, Andrea Califano, Elisa de Stanchina, Filemon Dela Cruz, Andrew L Kung, Mrinal M Gounder, Alex Kentsis
Epigenetic targeting of PGBD5-dependent DNA damage in SMARCB1-deficient sarcomas. bioRxiv : the preprint server for biology (2024)
Yaniv Kazansky, Daniel Cameron, Helen S Mueller, Phillip Demarest, Nadia Zaffaroni, Noemi Arrighetti, Valentina Zuco, Yasumichi Kuwahara, Romel Somwar, Marc Ladanyi, Rui Qu, Elisa De Stanchina, Filemon Dela Cruz, Andrew L Kung, Mrinal M Gounder, Alex Kentsis
Overcoming Clinical Resistance to EZH2 Inhibition Using Rational Epigenetic Combination Therapy. Cancer discovery 14 (6) (2024)
Makiko Yamada, Ross R Keller, Rodrigo Lopez Gutierrez, Daniel Cameron, Hiromichi Suzuki, Reeti Sanghrajka, Jake Vaynshteyn, Jeffrey Gerwin, Francesco Maura, William Hooper, Minita Shah, Nicolas Robine, Phillip Demarest, N Sumru Bayin, Luz Jubierre Zapater, Casie Reed, Steven Hébert, Ignas Masilionis, Ronan Chaligné, Nicholas D Socci, Michael D Taylor, Claudia L Kleinman, Alexandra L Joyner, G Praveen Raju, Alex Kentsis
Childhood cancer mutagenesis caused by transposase-derived PGBD5. Science advances 10 (12) (2024)
Yaniv Kazansky, Daniel Cameron, Helen S Mueller, Phillip Demarest, Nadia Zaffaroni, Noemi Arrighetti, Valentina Zuco, Yasumichi Kuwahara, Romel Somwar, Marc Ladanyi, Rui Qu, Elisa De Stanchina, Filemon Dela Cruz, Andrew L Kung, Mrinal M Gounder, Alex Kentsis
Overcoming Clinical Resistance to EZH2 Inhibition Using Rational Epigenetic Combination Therapy. Cancer discovery 14 (6) (2024)
Makiko Yamada, Ross R Keller, Rodrigo Lopez Gutierrez, Daniel Cameron, Hiromichi Suzuki, Reeti Sanghrajka, Jake Vaynshteyn, Jeffrey Gerwin, Francesco Maura, William Hooper, Minita Shah, Nicolas Robine, Phillip Demarest, N Sumru Bayin, Luz Jubierre Zapater, Casie Reed, Steven Hébert, Ignas Masilionis, Ronan Chaligné, Nicholas D Socci, Michael D Taylor, Claudia L Kleinman, Alexandra L Joyner, G Praveen Raju, Alex Kentsis
Childhood cancer mutagenesis caused by transposase-derived PGBD5. Science advances 10 (12) (2024)
Yaniv Kazansky, Helen S Mueller, Daniel Cameron, Phillip Demarest, Nadia Zaffaroni, Noemi Arrighetti, Valentina Zuco, Prabhjot S Mundi, Yasumichi Kuwahara, Romel Somwar, Rui Qu, Andrea Califano, Elisa de Stanchina, Filemon Dela Cruz, Andrew L Kung, Mrinal M Gounder, Alex Kentsis
Epigenetic targeting of PGBD5-dependent DNA damage in SMARCB1-deficient sarcomas. bioRxiv : the preprint server for biology (2024)
Ning Wang, Nicole A Mcneer, Elliot O Eton, Josh Fass, Alex Kentsis
Proteomic Barcoding Platform for Macromolecular Screening and Delivery. Journal of proteome research (2024)
Ning Wang, Nicole A Mcneer, Elliot O Eton, Josh Fass, Alex Kentsis
Proteomic Barcoding Platform for Macromolecular Screening and Delivery. Journal of proteome research 23 (6) (2024)
Yaniv Kazansky, Daniel Cameron, Helen S Mueller, Phillip Demarest, Nadia Zaffaroni, Noemi Arrighetti, Valentina Zuco, Yasumichi Kuwahara, Romel Somwar, Marc Ladanyi, Rui Qu, Elisa De Stanchina, Filemon Dela Cruz, Andrew L Kung, Mrinal M Gounder, Alex Kentsis
Overcoming clinical resistance to EZH2 inhibition using rational epigenetic combination therapy. Cancer discovery (2024)
Yaniv Kazansky, Daniel Cameron, Helen S Mueller, Phillip Demarest, Nadia Zaffaroni, Noemi Arrighetti, Valentina Zuco, Yasumichi Kuwahara, Romel Somwar, Marc Ladanyi, Rui Qu, Elisa De Stanchina, Filemon Dela Cruz, Andrew L Kung, Mrinal M Gounder, Alex Kentsis
Overcoming Clinical Resistance to EZH2 Inhibition Using Rational Epigenetic Combination Therapy. Cancer discovery 14 (6) (2024)
Makiko Yamada, Ross R Keller, Rodrigo Lopez Gutierrez, Daniel Cameron, Hiromichi Suzuki, Reeti Sanghrajka, Jake Vaynshteyn, Jeffrey Gerwin, Francesco Maura, William Hooper, Minita Shah, Nicolas Robine, Phillip Demarest, N Sumru Bayin, Luz Jubierre Zapater, Casie Reed, Steven Hébert, Ignas Masilionis, Ronan Chaligné, Nicholas D Socci, Michael D Taylor, Claudia L Kleinman, Alexandra L Joyner, G Praveen Raju, Alex Kentsis
Childhood cancer mutagenesis caused by transposase-derived PGBD5. Science advances 10 (12) (2024)
Yaniv Kazansky, Daniel Cameron, Helen S Mueller, Phillip Demarest, Nadia Zaffaroni, Noemi Arrighetti, Valentina Zuco, Yasumichi Kuwahara, Romel Somwar, Marc Ladanyi, Rui Qu, Elisa De Stanchina, Filemon Dela Cruz, Andrew L Kung, Mrinal M Gounder, Alex Kentsis
Overcoming clinical resistance to EZH2 inhibition using rational epigenetic combination therapy. Cancer discovery (2024)
Yaniv Kazansky, Daniel Cameron, Helen S Mueller, Phillip Demarest, Nadia Zaffaroni, Noemi Arrighetti, Valentina Zuco, Yasumichi Kuwahara, Romel Somwar, Marc Ladanyi, Rui Qu, Elisa De Stanchina, Filemon Dela Cruz, Andrew L Kung, Mrinal M Gounder, Alex Kentsis
Overcoming Clinical Resistance to EZH2 Inhibition Using Rational Epigenetic Combination Therapy. Cancer discovery 14 (6) (2024)
Yaniv Kazansky, Daniel Cameron, Helen S Mueller, Phillip Demarest, Nadia Zaffaroni, Noemi Arrighetti, Valentina Zuco, Yasumichi Kuwahara, Romel Somwar, Marc Ladanyi, Rui Qu, Elisa De Stanchina, Filemon Dela Cruz, Andrew L Kung, Mrinal M Gounder, Alex Kentsis
Overcoming clinical resistance to EZH2 inhibition using rational epigenetic combination therapy. Cancer discovery (2024)
Yaniv Kazansky, Daniel Cameron, Helen S Mueller, Phillip Demarest, Nadia Zaffaroni, Noemi Arrighetti, Valentina Zuco, Yasumichi Kuwahara, Romel Somwar, Marc Ladanyi, Rui Qu, Elisa De Stanchina, Filemon Dela Cruz, Andrew L Kung, Mrinal M Gounder, Alex Kentsis
Overcoming Clinical Resistance to EZH2 Inhibition Using Rational Epigenetic Combination Therapy. Cancer discovery 14 (6) (2024)
Luz Jubierre Zapater, Elias Rodriguez-Fos, Merce Planas-Felix, Sara Lewis, Daniel Cameron, Phillip Demarest, Anika Nabila, Junfei Zhao, Paul Bergin, Casie Reed, Makiko Yamada, Nicholas D Socci, Matthew Hayes, Raúl Rabadán, David Torrents, Michael C Kruer, Miklos Toth, Alex Kentsis
A transposase-derived gene required for human brain development. bioRxiv : the preprint server for biology (2023)
Nathaniel Kwok, Zita Aretz, Sumiko Takao, Zheng Ser, Paolo Cifani, Alex Kentsis
Integrative proteogenomics using ProteomeGenerator2. bioRxiv : the preprint server for biology (2023)
Luz Jubierre Zapater, Elias Rodriguez-Fos, Merce Planas-Felix, Sara Lewis, Daniel Cameron, Phillip Demarest, Anika Nabila, Junfei Zhao, Paul Bergin, Casie Reed, Makiko Yamada, Nicholas D Socci, Matthew Hayes, Raúl Rabadán, David Torrents, Michael C Kruer, Miklos Toth, Alex Kentsis
A transposase-derived gene required for human brain development. bioRxiv : the preprint server for biology (2023)
Yaniv Kazansky, Daniel Cameron, Phillip Demarest, Nadia Zaffaroni, Noemi Arrighetti, Valentina Zuco, Yasumichi Kuwahara, Rui Qu, Elisa De Stanchina, Filemon Dela Cruz, Andrew Kung, Mrinal Gounder, Alex Kentsis
Overcoming clinical resistance to EZH2 inhibition using rational epigenetic combination therapy. bioRxiv : the preprint server for biology (2023)
Yaniv Kazansky, Alex Kentsis
Epigenetic Cooperativity as a Therapeutic Vulnerability in Cancer. Cancer research 83 (23) (2023)
Nathaniel Kwok, Zita E H Aretz, Sumiko Takao, Zheng Ser, Paolo Cifani, Alex Kentsis
Integrative Proteogenomics Using ProteomeGenerator2. Journal of proteome research (2023)
Paolo Cifani, Alex Kentsis
Quantitative Cell Proteomic Atlas: Pathway-Scale Targeted Mass Spectrometry for High-Resolution Functional Profiling of Cell Signaling. Journal of proteome research 21 (10) (2022)
Leonie Smeenk, Sophie Ottema, Roger Mulet-Lazaro, Anja Ebert, Marije Havermans, Andrea Arricibita Varea, Michaela Fellner, Dorien Pastoors, Stanley van Herk, Claudia Erpelinck-Verschueren, Tim Grob, Remco M Hoogenboezem, François G Kavelaars, Daniel R Matson, Eric M J Bindels, Alex Kentsis, Johannes Zuber, Ruud Delwel
Selective Requirement of MYB for Oncogenic Hyperactivation of a Translocated Enhancer in Leukemia. Cancer discovery 11 (11) (2021)
Sumiko Takao, Lauren Forbes, Masahiro Uni, Shuyuan Cheng, Jose Mario Bello Pineda, Yusuke Tarumoto, Paolo Cifani, Gerard Minuesa, Celine Chen, Michael G Kharas, Robert K Bradley, Christopher R Vakoc, Richard P Koche, Alex Kentsis
Convergent organization of aberrant MYB complex controls oncogenic gene expression in acute myeloid leukemia. eLife 10 (2021)
You Yu, Shibai Li, Zheng Ser, Tanmoy Sanyal, Koyi Choi, Bingbing Wan, Huihui Kuang, Andrej Sali, Alex Kentsis, Dinshaw J Patel, Xiaolan Zhao
Integrative analysis reveals unique structural and functional features of the Smc5/6 complex. Proceedings of the National Academy of Sciences of the United States of America 118 (19) (2021)
Paolo Cifani, Zhi Li, Danmeng Luo, Mark Grivainis, Andrew M Intlekofer, David Fenyo, Alex Kentsis
Discovery of Protein Modifications Using Differential Tandem Mass Spectrometry Proteomics. Journal of proteome research 20 (4) (2021)
Alex Kentsis
Why do young people get cancer? Pediatric blood & cancer 67 (7) (2020)
Nicole A McNeer, John Philip, Heather Geiger, Rhonda E Ries, Vincent-Philippe Lavallée, Michael Walsh, Minita Shah, Kanika Arora, Anne-Katrin Emde, Nicolas Robine, Todd A Alonzo, E Anders Kolb, Alan S Gamis, Malcolm A Smith, Daniela Se Gerhard, Jaime Guidry-Auvil, Soheil Meshinchi, Alex Kentsis
Genetic mechanisms of primary chemotherapy resistance in pediatric acute myeloid leukemia. Leukemia 33 (8) (2019)
Zheng Ser, Paolo Cifani, Alex Kentsis
Optimized Cross-Linking Mass Spectrometry for in Situ Interaction Proteomics. Journal of proteome research 18 (6) (2019)
Alejandro Gutierrez, Alex Kentsis
Acute myeloid/T-lymphoblastic leukaemia (AMTL): a distinct category of acute leukaemias with common pathogenesis in need of improved therapy. British journal of haematology 180 (6) (2018)
Paolo Cifani, Avantika Dhabaria, Zining Chen, Akihide Yoshimi, Emily Kawaler, Omar Abdel-Wahab, John T Poirier, Alex Kentsis
ProteomeGenerator: A Framework for Comprehensive Proteomics Based on de Novo Transcriptome Assembly and High-Accuracy Peptide Mass Spectral Matching. Journal of proteome research 17 (11) (2018)
Kavitha Ramaswamy, Lauren Forbes, Gerard Minuesa, Tatyana Gindin, Fiona Brown, Michael Gregory Kharas, Andrei V Krivtsov, Scott A Armstrong, Eric Still, Elisa de Stanchina, Birgit Knoechel, Richard Koche, Alex Kentsis
Peptidomimetic blockade of MYB in acute myeloid leukemia. Nature communications 9 (1) (2018)
Darren C Johnson, Cornelius Y Taabazuing, Marian C Okondo, Ashley J Chui, Sahana D Rao, Fiona C Brown, Casie Reed, Elizabeth Peguero, Elisa de Stanchina, Alex Kentsis, Daniel A Bachovchin
DPP8/DPP9 inhibitor-induced pyroptosis for treatment of acute myeloid leukemia. Nature medicine 24 (8) (2018)
Anton G Henssen, Casie Reed, Eileen Jiang, Heathcliff Dorado Garcia, Jennifer von Stebut, Ian C MacArthur, Patrick Hundsdoerfer, Jun Hyun Kim, Elisa De Stanchina, Yasumichi Kuwahara, Hajime Hosoi, Neil J Ganem, Filemon Dela Cruz, Andrew L Kung, Johannes H Schulte, John H J Petrini, Alex Kentsis
Therapeutic targeting of PGBD5-induced DNA repair dependency in pediatric solid tumors. Science translational medicine 9 (414) (2018)
Anton G Henssen, Richard Koche, Jiali Zhuang, Eileen Jiang, Casie Reed, Amy Eisenberg, Eric Still, Ian C MacArthur, Elias Rodríguez-Fos, Santiago Gonzalez, Montserrat Puiggròs, Andrew N Blackford, Christopher E Mason, Elisa de Stanchina, Mithat Gönen, Anne-Katrin Emde, Minita Shah, Kanika Arora, Catherine Reeves, Nicholas D Socci, Elizabeth Perlman, Cristina R Antonescu, Charles W M Roberts, Hanno Steen, Elizabeth Mullen, Stephen P Jackson, David Torrents, Zhiping Weng, Scott A Armstrong, Alex Kentsis
PGBD5 promotes site-specific oncogenic mutations in human tumors. Nature genetics 49 (7) (2017)
Paolo Cifani, Mojdeh Shakiba, Sagar Chhangawala, Alex Kentsis
ProteoModlR for functional proteomic analysis. BMC bioinformatics 18 (1) (2017)
Fiona C Brown, Paolo Cifani, Esther Drill, Jie He, Eric Still, Shan Zhong, Sohail Balasubramanian, Dean Pavlick, Bahar Yilmazel, Kristina M Knapp, Todd A Alonzo, Soheil Meshinchi, Richard M Stone, Steven M Kornblau, Guido Marcucci, Alan S Gamis, John C Byrd, Mithat Gonen, Ross L Levine, Alex Kentsis
Genomics of primary chemoresistance and remission induction failure in paediatric and adult acute myeloid leukaemia. British journal of haematology 176 (1) (2016)
Anton G Henssen, Eileen Jiang, Jiali Zhuang, Luca Pinello, Nicholas D Socci, Richard Koche, Mithat Gonen, Camila M Villasante, Scott A Armstrong, Daniel E Bauer, Zhiping Weng, Alex Kentsis
Forward genetic screen of human transposase genomic rearrangements. BMC genomics 17 (2016)
J Etchin, J Montero, A Berezovskaya, B T Le, Alex Kentsis, A L Christie, A S Conway, W C Chen, C Reed, M R Mansour, C E L Ng, S Adamia, S J Rodig, I A Galinsky, R M Stone, B Klebanov, Y Landesman, M Kauffman, S Shacham, A L Kung, J C Y Wang, A Letai, A T Look
Activity of a selective inhibitor of nuclear export, selinexor (KPT-330), against AML-initiating cells engrafted into immunosuppressed NSG mice. Leukemia 30 (1) (2015)
Anton G Henssen, Elizabeth Henaff, Eileen Jiang, Amy R Eisenberg, Julianne R Carson, Camila M Villasante, Mondira Ray, Eric Still, Melissa Burns, Jorge Gandara, Cedric Feschotte, Christopher E Mason, Alex Kentsis
Genomic DNA transposition induced by human PGBD5. eLife 4 (2015)
S F McGee, S M Kornblau, Y Qiu, A T Look, N Zhang, S-Y Yoo, K R Coombes, Alex Kentsis
Biological properties of ligand-dependent activation of the MET receptor kinase in acute myeloid leukemia. Leukemia 29 (5) (2014)