Intravitreal metoprolol for circumscribed choroidal hemangiomas: a phase I clinical trial.
Leandro J ChavesAndré MessiasZélia M CorreaRodrigo JorgePublished in: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie (2021)
Patients with CCH treated with a single injection of 50μg/0.05ml intravitreal metoprolol injections showed no signs of acute ocular toxicity. This pilot study did not assess long-term retinal toxicity, different concentrations, drug resistance, and complications from repeated-intravitreal injections.
Keyphrases
- diabetic retinopathy
- age related macular degeneration
- vascular endothelial growth factor
- optical coherence tomography
- clinical trial
- ultrasound guided
- optic nerve
- oxidative stress
- platelet rich plasma
- liver failure
- respiratory failure
- risk factors
- drug induced
- open label
- study protocol
- phase ii
- randomized controlled trial
- double blind