Placebo response rates in randomized controlled trials for perianal Crohn's disease: A systematic review and meta-analysis.

Tanmay SharmaChristopher Ma Rocio SedanoJurij HanzelCassandra McDonaldMalcolm HoganGursimran S KochharNeeraj NarulaLaurent Peyrin-BirouletSilvio DaneseJohn K MacDonaldVipul Jairath

Published in: Journal of Crohn's & colitis (2022)

Placebo response and remission rates in pCD trials are influenced by patient and disease-related factors, as well as the type of intervention being studied. These contemporary rates will inform trial design for novel therapeutics.

Keyphrases

randomized controlled trial
phase iii
study protocol
clinical trial
double blind
case report
rheumatoid arthritis
systemic lupus erythematosus
disease activity
meta analyses