Use of Tissue Plasminogen Activator in Abdominal Abscesses in Children-A Single-Center Randomized Control Trial.
Craig R GibsonAfsaneh AmirabadiSimal GomanNicholas C ArmstrongJacob C LangerJoao G AmaralMichael J TempleDimitri A ParraPhilip R JohnBairbre L ConnollyPublished in: Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes (2020)
No significant difference in the length of catheter dwell time, procedure time to discharge, or time to resolution was found. Intracavitary tPA was not associated with morbidity or mortality. The results neither support nor negate routine use of tPA in the drainage of intra-abdominal abscess in children. It is possible that a multicentre study with a larger number of patients may answer this question more definitively.
Keyphrases
- end stage renal disease
- young adults
- chronic kidney disease
- newly diagnosed
- ejection fraction
- open label
- ultrasound guided
- double blind
- prognostic factors
- peritoneal dialysis
- cardiovascular events
- minimally invasive
- clinical practice
- patient reported outcomes
- randomized controlled trial
- single molecule
- coronary artery disease
- phase iii
- type diabetes
- rare case