An integrated meta-analysis approach to identifying medications with potential to alter breast cancer risk through connectivity mapping.
Gayathri ThillaiyampalamFabio LiberanteLiam MurrayChris CardwellKenneth Ian MillsShu-Dong ZhangPublished in: BMC bioinformatics (2017)
A few candidate drugs with potential to enhance breast cancer or increase the risk of the disease were also identified; further investigation on a large population is required to firmly establish their effects on breast cancer risks. This work thus provides a novel approach and an applicable example for identifying medications with potential to alter cancer risks through gene expression connectivity mapping.